I have been scientifically studying the traits and dispositions of the “lower animals” (so-called,) and contrasting them with the traits and dispositions of man. I find the result profoundly humiliating to me. For it obliges me to renounce my allegiance to the Darwinian theory of the Ascent of Man from the Lower Animals; since it now seems plain to me that that theory ought to be vacated in favor of a new and truer one, this new and truer one to be named the Descent of Man from the Higher Animals.

I would like to start by emphasizing the importance of surfaces. It is at a surface where many of our most interesting and useful phenomena occur. We live for example on the surface of a planet. It is at a surface where the catalysis of chemical reactions occur. It is essentially at a surface of a plant that sunlight is converted to a sugar. In electronics, most if not all active circuit elements involve non-equilibrium phenomena occurring at surfaces. Much of biology is concerned with reactions at a surface.

Man wants to see nature and evolution as separate from human activities. There is a natural world, and there is man. But man also belongs to the natural world. If he is a ferocious predator, that too is part of evolution. If cod and haddock and other species cannot survive because man kills them, something more adaptable will take their place. Nature, the ultimate pragmatist, doggedly searches for something that works. But as the cockroach demonstrates, what works best in nature does not always appeal to us.

Few scientists acquainted with the chemistry of biological systems at the molecular level can avoid being inspired. Evolution has produced chemical compounds exquisitely organized to accomplish the most complicated and delicate of tasks. Many organic chemists viewing crystal structures of enzyme systems or nucleic acids and knowing the marvels of specificity of the immune systems must dream of designing and synthesizing simpler organic compounds that imitate working features of these naturally occurring compounds.

For those scientists who take it seriously, Darwinian evolution has functioned more as a philosophical belief system than as a testable scientific hypothesis. This quasi-religious function of the theory is, I think, what lies behind many of the extreme statements that you have doubtless encountered from some scientists opposing any critical analysis of neo-Darwinism in the classroom. It is also why many scientists make public statements about the theory that they would not defend privately to other scientists like me.

It is often thought that the life of the hunter-gatherer was one of feast and famine. But most available data suggest that they were surprisingly healthy and had a fairly stable diet and lifestyle. Not so the primitive farmers. In years when the crops failed, in settlements where the population density was high and where disease weakened the ability to cope even further, life would have been very hard indeed. The settled population could not migrate to follow the food supply as could hunter-gatherers. They were trapped.

Not only in antiquity but in our own times also laws have been passed...to secure good conditions for workers; so it is right that the art of medicine should contribute its portion for the benefit and relief of those for whom the law has shown such foresight...[We] ought to show peculiar zeal...in taking precautions for their safety. I for one have done all that lay in my power, and have not thought it beneath me to step into workshops of the meaner sort now and again and study the obscure operations of mechanical arts.

A sound Physics of the Earth should include all the primary considerations of the earth's atmosphere, of the characteristics and continual changes of the earth's external crust, and finally of the origin and development of living organisms. These considerations naturally divide the physics of the earth into three essential parts, the first being a theory of the atmosphere, or Meteorology, the second, a theory of the earth's external crust, or Hydrogeology, and the third, a theory of living organisms, or Biology.

The very comprehensibility of the world points to an intelligence behind the world. Indeed, science would be impossible if our intelligence were not adapted to the intelligibility of the world. The match between our intelligence and the intelligibility of the world is no accident. Nor can it properly be attributed to natural selection, which places a premium on survival and reproduction and has no stake in truth or conscious thought. Indeed, meat-puppet robots are just fine as the output of a Darwinian evolutionary process.

The tendency to variation in living beings, which all admitted as a matter of fact; the selective influence of conditions, which no one could deny to be a matter of fact, when his attention was drawn to the evidence; and the occurrence of great geological changes which also was matter of fact; could be used as the only necessary postulates of a theory of the evolution of plants and animals which, even if not at once, competent to explain all the known facts of biological science, could not be shown to be inconsistent with any.

If, again, the most superficial introspection teaches the physiologist that his conscious life is dependent upon the mechanical adjustments of his body, and that inversely his body is subjected with certain limitations to his will, then it only remains for him to make one assumption more, namely, that this mutual interdependence between the spiritual and the material is itself also dependent on law, and he has discovered the bond by which the science of the matter and the science of consciousness are united into a single whole.

This little book has been written in the hope that it may appeal to several classes of readers.Not infrequently I have been asked by friends of different callings in life to recommend them some book on mimicry which shall be reasonably short, well illustrated without being very costly, and not too hard to understand. I have always been obliged to tell them that I know of nothing in our language answering to this description, and it is largely as an attempt to remedy this deficiency that the present little volume has been written.

Our brains contain one hundred billion nerve cells (neurons). Each neuron makes links with ten thousand other neurons to form an incredible three dimensional grid. This grid therefore contains a thousand trillion connections - that's 1,000,000,000,000,000 (a quadrillion). It's hard to imagine this, so let's visualise each connection as a disc that's 1mm thick. Stack up the quadrillion discs on top of each other and they will reach the sun (which is ninety-three million miles from the earth) and back, three times over.

The following proposition seems to me in a high degree probable—namely, that any animal whatever, endowed with well-marked social instincts, the parental and filial affections being here included, would inevitably acquire a moral sense or conscience, as soon as its intellectual powers had become as well, or nearly as well developed, as in man. For, firstly, the social instincts lead an animal to take pleasure in the society of its fellows, to feel a certain amount of sympathy with them, and to perform various services for them.

Molecular biology has shown that even the simplest of all living systems on the earth today, bacterial cells, are exceedingly complex objects. Although the tiniest bacterial cells are incredibly small, weighing less than 10-12 gms, each is in effect a veritable micro-miniaturized factory containing thousands of exquisitely designed pieces of intricate molecular machinery, made up altogether of one hundred thousand million atoms, far more complicated than any machine built by man and absolutely without parallel in the nonliving world.