Must the interest of life wane for us all as the progress of knowledge curtails the playground of imagination? No doubt it must in some measure, but there is another cause.I believe that in these days we have too many occupations, too many interests; we know too many things, and, if you will, have too many advantages and facilities. Our faculty of taking an interest is dissipated and frittered away.

Physical vision - one might say scientific vision - brings about a metaphysical shift in the observer's view of reality as a whole. The geography of the earth, or the structure of the solar system, are in an instant utterly changed, and forever. The explorer, the scientific observer, the literary reader, experience the Sublime: a moment of revelation into the idea of the unbounded, the infinite.

Prose Poems from my book SPANOBSERVATIONSo, we may not be able to explain the world. Not exactly. But we can accept it, and love it. We can turn our faces to the light and examine the minutest details simply for the sake of it. We can live lives of joy and purpose. We are all part of one whole. Take comfort in this. Almost every one of us is capable of holding a cup to another’s lips without our hands shaking.

The progress of science has always been the result of a close interplay between our concepts of the universe and our observations on nature. The former can only evolve out of the latter and yet the latter is also conditioned greatly by the former. Thus in our exploration of nature, the interplay between our concepts and our observations may sometimes lead to totally unexpected aspects among already familiar phenomena.

..he went to the kitchen to get a banana; after each mouthful he pulled back a fraction the four or five strips of striped skin, faded petals, which covered his fist as it clenched the base of the fruit; carefully he detached the friable, cardboard-flavoured filaments that run down its surface like meridian lines, in a word peeling his banana the way the anthropoid will forever peel his. He threw one of the filaments into the fly cage..

Science is not, as so many seem to think, something apart, which has to do with telescopes, retorts, and test-tubes, and especially with nasty smells, but it is a way of searching out by observation, trial and classification; whether the phenomena investigated be the outcome of human activities, or of the more direct workings of nature's laws. Its methods admit of nothing untidy or slip-shod; its keynote is accuracy and its goal is truth.

Another very good test some readers may want to look up, which we do not have space to describe here, is the Casimir effect, where forces between metal plates in empty space are modified by the presence of virtual particles.Thus virtual particles are indeed real and have observable effects that physicists have devised ways of measuring. Their properties and consequences are well established and well understood consequences of quantum mechanics.

Primary causes are unknown to us; but are subject to simple and constant laws, which may be discovered by observation, the study of them being the object of natural philosophy.Heat, like gravity, penetrates every substance of the universe, its rays occupy all parts of space. The object of our work is to set forth the mathematical laws which this element obeys. The theory of heat will hereafter form one of the most important branches of general physics.

Reason, Observation and Experience — the Holy Trinity of Science — have taught us that happiness is the only good; that the time to be happy is now, and the way to be happy is to make others so. This is enough for us. In this belief we are content to live and die. If by any possibility the existence of a power superior to, and independent of, nature shall be demonstrated, there will then be time enough to kneel. Until then, let us stand erect.

I observed on most collected stones the imprints of innumerable plant fragments which were so different from those which are growing in the Lyonnais, in the nearby provinces, and even in the rest of France, that I felt like collecting plants in a new world... The number of these leaves, the way they separated easily, and the great variety of plants whose imprints I saw, appeared to me just as many volumes of botany representing in the same quarry the oldest library of the world.

The extracellular genesis of cells in animals seemed to me, ever since the publication of the cell theory [of Schwann], just as unlikely as the spontaneous generation of organisms. These doubts produced my observations on the multiplication of blood cells by division in bird and mammalian embryos and on the division of muscle bundles in frog larvae. Since then I have continued these observations in frog larvae, where it is possible to follow the history of tissues back to segmentation.

However gross a man may be, the minute he expresses a strong and genuine affection, some inner secretion alters his features, animates his gestures, and colors his voice. The stupidest man will often, under the stress of passion, achieve heights of eloquence, in thought if not in language, and seem to move in some luminous sphere. Goriot's voice and gesture had at this moment the power of communication that characterizes the great actor. Are not our finer feelings the poems of the human will?

From the dawn of exact knowledge to the present day, observation, experiment, and speculation have gone hand in hand; and, whenever science has halted or strayed from the right path, it has been, either because its votaries have been content with mere unverified or unverifiable speculation (and this is the commonest case, because observation and experiment are hard work, while speculation is amusing); or it has been, because the accumulation of details of observation has for a time excluded speculation.

For if we are observed in all matters, we are constantly under threat of correction, judgment, criticism, even plagiarism of our own uniqueness. We become children, fettered under watchful eyes, constantly fearful that — either now or in the uncertain future — patterns we leave behind will be brought back to implicate us, by whatever authority has now become focused upon our once-private and innocent acts. We lose our individuality, because everything we do is observable and recordable."[The Eternal Value of Privacy, May 18, 2006]

Having always observed that most of them who constantly took in the weekly Bills of Mortality made little other use of them than to look at the foot how the burials increased or decreased, and among the Casualties what had happened, rare and extraordinary, in the week current; so as they might take the same as a Text to talk upon in the next company, and withal in the Plague-time, how the Sickness increased or decreased, that the Rich might judge of the necessity of their removal, and Trades-men might conjecture what doings they were likely to have in their respective dealings.