My laboratory is interested in the related challenges of understanding the origin of life on the early earth, and constructing synthetic cellular life in the laboratory. Focusing on artificial life frees us to explore novel chemical systems, but what we learn from these systems helps us to understand possible pathways leading to the origin of life. Our basic design for a synthetic cell involves the encapsulation of a spontaneously replicating nucleic acid, which acts as the genetic material, within a spontaneously replicating membrane vesicle, which provides spatial localization. We are using chemical synthesis to make nucleic acids with modified nucleobases and sugar-phosphate backbones.

The evolutionists, piercing beneath the show of momentary stability, discovered, hidden in rudimentary organs, the discarded rubbish of the past. They detected the reptile under the lifted feathers of the bird, the lost terrestrial limbs dwindling beneath the blubber of the giant cetaceans. They saw life rushing outward from an unknown center, just as today the astronomer senses the galaxies fleeing into the infinity of darkness. As the spinning galactic clouds hurl stars and worlds across the night, so life, equally impelled by the centrifugal powers lurking in the germ cell, scatters the splintered radiance of consciousness and sends it prowling and contending through the thickets of the world.

The more formidable the contradiction between inexhaustible life-joy and inevitable fate, the greater the longing which reveals itself in the kingdom of poetry and in the self-created world of dreams hopes to banish the dark power of reality. The gods enjoy eternal youth, and the search for the means of securing it was one of the occupations of the heroes of mythology and the sages, as it was of real adventurers in the middle ages and more recent times. . . . But the fountain of youth has not been found, and can not be found if it is sought in any particular spot on the earth. Yet it is no fable, no dream-picture; it requires no adept to find it: it streams forth inexhaustible in all living nature.

Teachers seeking to 'teach the controversy' over Darwinian evolution in today's climate will likely be met with false warnings that it is unconstitutional to say anything negative about Darwinian evolution. Students who attempt to raise questions about Darwinism, or who try to elicit from the teacher an honest answer about the status of intelligent design theory will trigger administrators' concerns about whether they stand in Constitutional jeopardy. A chilling effect on open inquiry is being felt in several states already, including Ohio. South Carolina, and Pennsylvania. [District Court] Judge Jones's message is clear: give Darwin only praise, or else face the wrath of the judiciary.

We need science education to produce scientists, but we need it equally to create literacy in the public. Man has a fundamental urge to comprehend the world about him, and science gives today the only world picture which we can consider as valid. It gives an understanding of the inside of the atom and of the whole universe, or the peculiar properties of the chemical substances and of the manner in which genes duplicate in biology. An educated layman can, of course, not contribute to science, but can enjoy and participate in many scientific discoveries which as constantly made. Such participation was quite common in the 19th century, but has unhappily declined. Literacy in science will enrich a person's life.

It was in the attempt to ascertain the interrelationships between species that experiments n genetics were first made. The words "evolution" and "origin of species" are now so intimately associated with the name of Darwin that we are apt to forger that the idea of common descent had been prominent in the mnds of naturalists before he wrote, and that, for more than half a century, zealous investigators had been devoting themselves to the experimental study of that possibility. Prominent among this group of experimenters may be mentioned Koelreauter, John Hunter, Herbert Knight, Gartner, Jordan. Naudin, Godron, Lecoq, Wichura--men whose names are familiar to every reader of Animals and Plants unders Domestication.

Evidently neither cats nor dogs, nor other animals that listen to human music, were constituted for the appreciation of it, for it is not of the slightest use to them in the struggle for existence. Moreover, they and their organs of hearing were much older than man and his music. Their power of appreciating music is therefore an uncontemplated side-faculty of a hearing apparatus which has become on other grounds what we find it to be. So it is, I believe, with man. He has not acquired his musical hearing as such, but has received a highly developed organ of hearing by a process of selection, because it was necessary to him in the selective process ; and this organ of hearing happens also to be adapted to listening to music.

An evolutionary perspective of our place in the history of the earth reminds us that Homo sapiens sapiens has occupied the planet for the tiniest fraction of that planet's four and a half thousand million years of existence. In many ways we are a biological accident, the product of countless propitious circumstances. As we peer back through the fossil record, through layer upon layer of long-extinct species, many of which thrived far longer than the human species is ever likely to do, we are reminded of our mortality as a species. There is no law that declares the human animal to be different, as seen in this broad biological perspective, from any other animal. There is no law that declares the human species to be immortal.

The Everglades was the only place on earth where alligators (broad snout, fresh water, darker skin) and crocodiles (pointy snout, salt water, toothy grin) lived side by side. It was the only home of the Everglades mink, Okeechobee gourd, and Big Cypress fox squirrel. It had carnivorous plants, amphibious birds, oysters that grew on trees, cacti that grew in water, lizards that changed colors, and fish that changed genders. It had 1,100 species of trees and plants, 350 birds, and 52 varieties of porcelain-smooth, candy-striped tree snails. It had bottlenose dolphins, marsh rabbits, ghost orchids, moray eels, bald eagles, and countless other species that didn't seem to belong on the same continent, much less in the same ecosystem.

Individual humans are not super, but the organism of which we are all tiny cellular parts is most certainly that. The life-form that's so big we forget it's there, that turns minerals on its planet into tools to touch the infinite black gap between stars or probe the obliterating pressures at the bottom of the oceans. We are already part of a superbeing, a monster, a god, a living process that is so all encompassing that it is to an individual life what water is to a fish. We are cells in the body of a three-billion-year-old life-form whose roots are in the Precambrian oceans and whose genetic wiring extends through the living structures of everything on the planet, connecting everything that has ever lived in one immense nervous system.

...on opening the incubator I experienced one of those rare moments of intense emotion which reward the research worker for all his pains: at first glance I saw that the broth culture, which the night before had been very turbid was perfectly clear: all the bacteria had vanished... as for my agar spread it was devoid of all growth and what caused my emotion was that in a flash I understood: what causes my spots was in fact an invisible microbe, a filterable virus, but a virus parasitic on bacteria. Another thought came to me also, If this is true, the same thing will have probably occurred in the sick man. In his intestine, as in my test-tube, the dysentery bacilli will have dissolved away under the action of their parasite. He should now be cured.

The beauty in the genome is of course that it's so small. The human genome is only on the order of a gigabyte of data...which is a tiny little database. If you take the entire living biosphere, that's the assemblage of 20 million species or so that constitute all the living creatures on the planet, and you have a genome for every species the total is still about one petabyte, that's a million gigabytes - that's still very small compared with Google or the Wikipedia and it's a database that you can easily put in a small room, easily transmit from one place to another. And somehow mother nature manages to create this incredible biosphere, to create this incredibly rich environment of animals and plants with this amazingly small amount of data.

The living cell is the most complex system of its size known to mankind. Its host of specialized molecules, many found nowhere else but within living material, are themselves already enormously complex. They execute a dance of exquisite fidelity, orchestrated with breathtaking precision. Vastly more elaborate than the most complicated ballet, the dance of life encompasses countless molecular performers in synergetic coordination. Yet this is a dance with no sign of a choreographer. No intelligent supervisor, no mystic force, no conscious controlling agency swings the molecules into place at the right time, chooses the appropriate players, closes the links, uncouples the partners, moves them on. The dance of life is spontaneous, self-sustaining, and self-creating.

Things that look like they were designed, probably were... If intelligence is an operative component of the universe, a science that methodologically excludes its existence will be susceptible to being trapped in an endless chase for materialistic causes that do not exist... Where there are sufficient grounds for inferring intelligent causation, based on evidence of "specified complexity," it should be considered as a component of scientific theories.Inclusion of intelligent causation in the scientific equation is not novel and has not impeded the practice of science in the past, e.g. Newton and Kepler, in an age when science was not constrained by a philosophical materialism, and by many current scientists who have remained open to following the evidence where it leads.

Among all the occurrences possible in the universe the a priori probability of any particular one of them verges upon zero. Yet the universe exists; particular events must take place in it, the probability of which (before the event) was infinitesimal. At the present time we have no legitimate grounds for either asserting or denying that life got off to but a single start on earth, and that, as a consequence, before it appeared its chances of occurring were next to nil. ... Destiny is written concurrently with the event, not prior to it... The universe was not pregnant with life nor the biosphere with man. Our number came up in the Monte Carlo game. Is it surprising that, like the person who has just made a million at the casino, we should feel strange and a little unreal?