The poem or the discovery exists in two moments of vision: the moment of appreciation as much as that of creation; for the appreciator must see the movement, wake to the echo which was started in the creation of the work. In the moment of appreciation we live again the moment when the creator saw and held the hidden likeness. When a simile takes us aback and persuades us together, when we find a juxtaposition in a picture both odd and intriguing, when a theory is at once fresh and convincing, we do not merely nod over someone else's work. We re-enact the creative act, and we ourselves make the discovery again......Reality is not an exhibit for man's inspection, labeled: "Do not touch." There are no appearances to be photographed, no experiences to be copied, in which we do not take part. We re-make nature by the act of discovery, in the poem or in the theorem. And the great poem and the deep theorem are new to every reader, and yet are his own experiences, because he himself re-creates them. They are the marks of unity in variety; and in the instant when the mind seizes this for itself, in art or in science, the heart misses a beat.

How did I discover saccharin? Well, it was partly by accident and partly by study. I had worked a long time on the compound radicals and substitution products of coal tar... One evening I was so interested in my laboratory that I forgot about my supper till quite late, and then rushed off for a meal without stopping to wash my hands. I sat down, broke a piece of bread, and put it to my lips. It tasted unspeakably sweet. I did not ask why it was so, probably because I thought it was some cake or sweetmeat. I rinsed my mouth with water, and dried my moustache with my napkin, when, to my surprise the napkin tasted sweeter than the bread. Then I was puzzled. I again raised my goblet, and, as fortune would have it, applied my mouth where my fingers had touched it before. The water seemed syrup. It flashed on me that I was the cause of the singular universal sweetness, and I accordingly tasted the end of my thumb, and found it surpassed any confectionery I had ever eaten. I saw the whole thing at once. I had discovered some coal tar substance which out-sugared sugar. I dropped my dinner, and ran back to the laboratory. There, in my excitement, I tasted the contents of every beaker and evaporating dish on the table.

The discovery of an interaction among the four hemes made it obvious that they must be touching, but in science what is obvious is not necessarily true. When the structure of hemoglobin was finally solved, the hemes were found to lie in isolated pockets on the surface of the subunits. Without contact between them how could one of them sense whether the others had combined with oxygen? And how could as heterogeneous a collection of chemical agents as protons, chloride ions, carbon dioxide, and diphosphoglycerate influence the oxygen equilibrium curve in a similar way? It did not seem plausible that any of them could bind directly to the hemes or that all of them could bind at any other common site, although there again it turned out we were wrong. To add to the mystery, none of these agents affected the oxygen equilibrium of myoglobin or of isolated subunits of hemoglobin. We now know that all the cooperative effects disappear if the hemoglobin molecule is merely split in half, but this vital clue was missed. Like Agatha Christie, Nature kept it to the last to make the story more exciting. There are two ways out of an impasse in science: to experiment or to think. By temperament, perhaps, I experimented, whereas Jacques Monod thought.

The rock I'd seen in my life looked dull because in all ignorance I'd never thought to knock it open. People have cracked ordinary New England pegmatite - big, coarse granite - and laid bare clusters of red garnets, or topaz crystals, chrysoberyl, spodumene, emerald. They held in their hands crystals that had hung in a hole in the dark for a billion years unseen. I was all for it. I would lay about me right and left with a hammer, and bash the landscape to bits. I would crack the earth's crust like a piñata and spread to the light the vivid prizes in chunks within. Rock collecting was opening the mountains. It was like diving through my own interior blank blackness to remember the startling pieces of a dream: there was a blue lake, a witch, a lighthouse, a yellow path. It was like poking about in a grimy alley and finding an old, old coin. Nothing was at it seemed. The earth was like a shut eye. Mother's not dead, dear - she's only sleeping. Pry open the thin lid and find a crystalline intelligence inside, a rayed and sidereal beauty. Crystals grew inside rock like arithmetical flowers. They lengthened and spread, adding plane to plane in awed and perfect obedience to an absolute geometry that even the stones - maybe only the stones - understood.

I remember when we found the first population of living Cerion agassizi in central Eleuthera. Our hypothesis of Cerion's general pattern required that two predictions be affirmed (or else we were in trouble): this population must disappear by hybridization with mottled shells toward bank-interior coasts and with ribby snails toward the bank-edge. We hiked west toward the bank-interior and easily found hybrids right on the verge of the airport road. We then moved east toward the bank-edge along a disused road with vegetation rising to five feet in the center between the tire paths. We should have found our hybrids but we did not. The Cerion agassizi simply stopped about two hundred yards north of our first ribby Cerion. Then we realized that a pond lay just to our east and that ribby forms, with their coastal preferences, might not favor the western side of the pond. We forded the pond and found a classic hybrid zone between Cerion agassizi and ribby Cerions. (Ribby Cerion had just managed to round the south end of the pond, but had not moved sufficiently north along the west side to establish contact with C. agassizi populations.) I wanted to shout for joy. Then I thought, "But who can I tell; who cares?" And I answered myself, "I don't have to tell anyone. We have just seen and understood something that no one has ever seen and understood before. What more does a man need?

If the people of Europe had known as much of astronomy and geology when the bible was introduced among them, as they do now, there never could have been one believer in the doctrine of inspiration. If the writers of the various parts of the bible had known as much about the sciences as is now known by every intelligent man, the book never could have been written. It was produced by ignorance, and has been believed and defended by its author. It has lost power in the proportion that man has gained knowledge. A few years ago, this book was appealed to in the settlement of all scientific questions; but now, even the clergy confess that in such matters, it has ceased to speak with the voice of authority. For the establishment of facts, the word of man is now considered far better than the word of God. In the world of science, Jehovah was superseded by Copernicus, Galileo, and Kepler. All that God told Moses, admitting the entire account to be true, is dust and ashes compared to the discoveries of Descartes, Laplace, and Humboldt. In matters of fact, the bible has ceased to be regarded as a standard. Science has succeeded in breaking the chains of theology. A few years ago, Science endeavored to show that it was not inconsistent with the bible. The tables have been turned, and now, Religion is endeavoring to prove that the bible is not inconsistent with Science. The standard has been changed.

-We need more love, to supersede hatred, -We need more strength, to resist our weaknesses, -We need more inspiration, to lighten up our innermind. -We need more learning, to erase our ignorance, -We need more wisdom, to live longer and happier, -We need more truths, to suppress deceptions, -We need more health, to enjoy our wealth, -We need more peace, to stay in harmony with our brethren -We need more smiles, to brighten up our day, -We need more hero's, and not zero's, -We need more change of ourselves, to change the lives of others, -We need more understanding, to tackle our misunderstanding, -We need more sympathy, not apathy, -We need more forgiveness, not vengeance, -We need more humility to be lifted up, -We need more patience and not undue eagerness, -We need more focus, to avoid distraction, -We need more optimism, not pessimism -We need more justice, not injustice, -We need more facts, not fiction,-We need more education, to curb illiteracy, -We need more skills, not incompetence, -We need more challenges, to make attempts, -We need more talents, to create the extraordinary, -We need more helping hands, not stingy folks, -We need more efforts, not laziness, -We need more jokes, to forget our worries, -We need more spirituality, not mean religion, -We need more freedom, not enslavement, -We need more peacemakers, not revolutionaries...with these, we create an heaven on earth.

Hive Queen: They never know anything. They don't have enough years in their little lives to come to an understanding of anything at all. And yet they think they understand. From earliest childhood, they delude themselves into thinking they comprehend the world, while all that's really going on is that they've got some primitive assumptions and prejudices. As they get older they learn a more elevated vocabulary in which to express their mindless pseudo- knowledge and bully other people into accepting their prejudices as if they were truth, but it all amounts to the same thing. Individually, human beings are all dolts.Pequenino: While collectively...Hive Queen: Collectively, they're a collection of dolts. But in all their scurrying around and pretending to be wise, throwing out idiotic half-understood theories about this and that, one or two of them will come up with some idea that is just a little bit closer to the truth than what was already known. And in a sort of fumbling trial and error, about half the time the truth actually rises to the top and becomes accepted by people who still don't understand it, who simply adopt it as a new prejudice to be trusted blindly until the next dolt accidentally comes up with an improvement.>Pequenino: So you're saying that no one is ever individually intelligent, and groups are even stupider than individuals-- and yet by keeping so many fools engaged in pretending to be intelligent, they still come up with some of the same results that an intelligent species would come up with.Hive Queen: Exactly.

The Biblical writers not only had no knowledge of these things, but they had a perverted concept of life and the universe. Their concept was that man was a victim of blood pollution and his only salvation was by a blood atonement.I remember once seeing a small pamphlet entitled, 'What the Bible Teaches about Morality.' On opening the little booklet, it was discovered to be nothing but blank pages! Another such pamphlet might very appropriately be published entitled, 'What the Bible Reveals about Disease, Medicine and Health,' and blank pages should be used for all the Bible contains about these vital subjects.On the contrary, these benefits have been denounced by the believers in the Bible, and by the representatives of the Bible's deity as being contrary to 'God's Plan.' Does not the Bible plainly state that only by the sweat of his brow is man to labor for the bread he eats? Here is the exact Biblical quotation: 'In the sweat of thy face thou shalt eat bread...' and why? Only because he sought knowledge.And does not the Bible God place a curse upon man for the knowledge that has been such a solace and benefit to him? Here is another exact Biblical quotation: '... cursed be the ground for thy sake; in pain thou shalt eat of it all the days of thy life.'The Bible is a lie.It is a fake and a fraud.I denounce this book and its God. I hold it in utter detestation.Every man and woman who has contributed to the relief of the pain and suffering of humanity has been an infidel to the Bible God! Every new invention, every new discovery for the benefit of man violates these Biblical edicts!I say, seek knowledge—defy this tyrant God—it is your only salvation.

Life is a great big beautiful three-ring circus. There are those on the floor making their lives among the heads of lions and hoops of fire, and those in the stands, complacent and wowed, their mouths stuffed with popcorn. I know less now than ever about life, but I do know its size. Life is enormous. Much grander than what we’ve taken for ourselves, so far. When the show is over and the tent is packed, the elephants, lions and dancing poodles are caged and mounted on trucks to caravan to the next town. The clown’s makeup has worn, and his bright, red smile has been washed down a sink. All that is left is another performance, another tent and set of lights. We rest in the knowledge: the show must go on. Somewhere, behind our stage curtain, a still, small voice asks why we haven’t yet taken up juggling. My seminars were like this. Only, instead of flipping shiny, black bowling balls or roaring chainsaws through the air, I juggled concepts. The world is intrinsically tied together. All things march through time at different intervals but move ahead in one fashion or another. Though we may never understand it, we are all part of something much larger than ourselves—something anchoring us to the spot we have mentally chosen. We sniff out the rules, through spiritual quests and the sciences. And with every new discovery, we grow more confused. Our inability to connect what seems illogical to unite and to defy logic in our understanding keeps us from enlightenment. The artists and insane tiptoe around such insights, but lack the compassion to hand-feed these concepts to a blind world. The interconnectedness of all things is not simply a pet phrase. It is a big “T” truth that the wise spend their lives attempting to grasp.